Supplementary Material for: Treatment of colorectal lung metastases: two centers retrospective study

Introduction Clear guidelines for colorectal lung metastases (LM) treatment are not available. This study aimed to provide insight in the treatment strategies and efficacy of local and systemic therapy in patients with LM eligible for (potentially) curative treatment. Material and methods This was a retrospective study of patients with ≤5 LM discussed in two tertiary referral centers. Patient and tumor characteristics were compared between treatment groups. Treatment strategies were compared between centers and survival data between treatment groups, local treatment modalities, and treating centers. Results Ninety-two patients (median 2 LM) were included. Seventy-one (77%) patients underwent local treatment (17 surgery, 13 ablation, 38 radiotherapy, 3 combination of local treatments) and 21 (23%) with systemic therapy alone. The latter group more frequently had extra pulmonary metastases (81.0% vs 26.8%, p